This course is designed to provide an examination of the physiological response and adaptations to acute and chronic exercise. Lectures integrate concepts from chemistry, biology, and physics to elucidate the mechanisms of exercise-induced physiological changes. Bioenergetics, metabolism, neuromuscular and endocrine control, and cardiorespiratory physiology are detailed in lecture. Emphasis will be placed on application through exercise testing and the evaluation of fitness in the laboratory component of this course. Exercise for special populations, training principles, nutrition, and environmental considerations will also be explored as they relate to health and human performance.